A Residue free green synergistic biopesticide Piper betle extract to supersede pesticide thiram

IJEP 42(11): 1376-1381 : Vol. 42 Issue. 11 (November 2022)

M.A. Sabitha* and A. Syed Mohamed

Sadakathullah Appa College (Autonomous), Department of Chemistry, Tirunelveli, Tamil Nadu- 627 011, India


Thiram (tetramethyldithiocarbamate) is used as fungicide and seed protectant in agriculture. It belongs to dithiocarbamate fungicides. The harmful effects of thiram include liver enlargement and dysfunction, degenerative changes, hepatitis and necrosis. Hence an alternative biopesticide to supersede thiram is essential. The Piper betle extract proves to be most economic, cost-effective and leaves no residue. It is easily biodegradable and available. Extract of betel leaves is very effective against pathogenic bacteria. The active component present in this extract is sterol which helps in the rupture of membrane structure of pathogens. The fungal infection occurs due to the hydrophobhicity of the cell surface which contains non-polar amino acids. The leaf extract reduces the hydrophobhicity and results in less adhesion of fungus. In the present study, the sample was subjected to evaluate biological activity of solvent extracts against fungal species, such as Fusarium sp. and Penicillium notatum. The high inhibition for Penicillium notatum and Fusarium solani in ethyl acetate extract proves that it can be used as effective fungicide against these fungi instead of thiram.


Thiram, Seed protectant, Fungicide, biopesticide, Piper betle


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