IJEP 43(1): 3-12 : Vol. 43 Issue. 1 (January 2023)
1. Amity University, Amity Institute of Microbial Technology, Noida, Uttar Pradesh – 201 301, India
2. Shriram Institute for Industrial Research, New Delhi – 110 007, India
Medicinal plants and probiotics both have very high potential in terms of their antimicrobial activity against antibiotic-resistant pathogenic enteric bacteria. Antibiotic resistance is one of the major problems in the medical world and sewage waters are the primary habitats to harbour antibiotic resistance bacteria (ARB), especially multi-drug resistance (MDR) human enteric pathogens. Micro-organisms have developed resistance to many commercial antibiotics due to the various uses of antibacterial drugs. The present study dealt with isolation, identification and characterization of human enteric pathogens from different sewage treatment plants located in Delhi. Initially samples were analyzed for the presence of pathogenic human enteric bacteria through morphological, biochemical and molecular analysis. The objective of the study was to evaluate the anti-microbial activity of Murraya koenigii and combination of Murraya koenigii with Lactobacillus plantarum which is commonly used probiotic against gastrointestinal disorders. Combining the effect of medicinal plant extract and probiotics may be a new approach due to their complementary antimicrobial effects and practically no side effects on human body. The synergistic effect of the Murraya koenigii leaf extract and probiotics will be necessarily higher than using them alone as antimicrobial product. Thus combination therapy could be effective for prevention of gastrointestinal infections and may be considered an alternative medicine to antibiotic regimens.
Sewage water, Murraya koenigii, Lactobacillus plantarum
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